Table 8 Selected results for TFs that are frequently mutated in cancer

II + IIIAB

Acetylation

48

26

1.823E-08

1.46E-07

0.125

Ubiquitination

47

27

2.08E-07

8.31E-07

0.118

Methylation

26

11

1.21E-05

3.23E-05

0.110

PF00856(SET)

6

0

1.21E-05

8.80E-03

0.164

PF13771(zf-HC5HC2H)

4

0

4.90E-05

1.78E-02

0.175

PF00628(PHD)

8

1

1.78E-04

2.58E-02

0.114

Sumoylation

14

5

1.14E-03

2.28E-0

0.082

O-GlcNAc

5

1

7.03E-03

1.12E-02

0.078

II

Acetylation

21

12

1.67E-03

1.33E-02

0.073

Ubiquitination

20

12

6.61E-03

2.64E-02

0.063

Methylation

11

5

1.23E-02

3.28E-02

0.062

O-GlcNAc

3

0

1.89E-02

3.78E-02

0.073

IIIB

Sumoylation

5

1

3.51E-03

2.80E-02

0.085

I + IIIAB

Ubiquitination

32

16

2.69E-07

2.15E-06

0.114

Acetylation

30

16

6.44E-06

2.12E-05

0.101

Methylation

19

7

7.94E-06

2.12E-05

0.114

PF00856(SET)

5

0

1.67E-05

5.78E-03

0.178

PF00628(PHD)

7

1

4.70E-05

8.56E-03

0.136

PF13771(zf-HC5HC2H)

3

0

3.17E-04

2.25E-02

0.168

Sumoylation

10

3

1.82E-03

3.64E-03

0.082

DNA_Binding

15

22

9.56E-03

1.53E-02

−0.061

IIIAB

Acetylation

27

14

5.47E-06

2.56E-05

0.102

Ubiquitination

27

14

6.39E-06

2.56E-05

0.101

PF00628(PHD)

6

0

1.82E-04

2.64E-02

0.125

PF00439(Bromodomain)

4

0

4.78E-04

4.35E-02

0.132

Methylation

15

6

2.79E-04

7.44E-04

0.091

Sumoylation

9

3

2.28E-03

4.56E-03

0.081

DNA_Binding

12

19

5.45E-03

8.71E-03

−0.065

I

Methylation

4

0

5.47E-03

4.38E-02

0.078