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Table 1 IC50 values (μM) of erlotinib treatment in three HNSCC cell lines (mean ± standard deviation)

From: The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines

Cell line

Normoxia

24 h hypoxia

72 h hypoxia

LICR-HN2

2.26 ± 0.83

1.06 ± 1.42

3.34 ± 1.25

LICR-HN5

1.16 ± 0.35

0.60 ± 0.23

1.49 ± 0.60

SC263

1.05 ± 0.12

0.95 ± 0.16

0.81 ± 0.12