Fig. 6
Lesion profiles of vole-adapted bovine scrapie at second and third passages and comparisons with other isolates. a Lesion profiles of vole-adapted P75-7 at second and third passages in voles in comparison with the two ‘sub-strains’ (17 and 18K) of vole-adapted CH1641. b Lesion profiles of vole-adapted P90-4 at second and third passages in voles in comparison with two natural scrapie isolates from sheep (SS-UK6 and SCR6). Scored neuroanatomical areas: 1 medulla, 2 cerebellum, 3 superior colliculus, 4 hypothalamus, 5 thalamus, 6 hippocampus, 7 septum, 8 retrosplenial and adjacent motor cortex, 9 cingulate and adjacent motor cortex.