Fig. 1

B-scan optical coherence tomography (OCT) and color fundus photography before and after treatment. a, b Findings in the right eye before intravitreal administration of ranibizumab for chronic branch retinal vein occlusion. Serous retinal detachment and macular edema were located at the outer retina. c, d Fluorescein angiography revealed a capillary nonperfusion area and dye leakage in the late phase. e, f Nine days after injection of ranibizumab, OCT and color fundus photography showed formation of a full thickness macular hole and decreasing intraretinal edema. g, h Five months after surgery, the macular hole was closed and macular edema decreased