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Fig. 3 | BMC Research Notes

Fig. 3

From: Derivation of induced pluripotent stem cells from orangutan skin fibroblasts

Fig. 3

Gene expression profiles of orangutan fibroblasts and candidate iPSCs. Dendrograms depicting unsupervised hierarchical clustering analysis of gene expression data from skin fibroblasts and iPSCs derived from orangutan donors. Donor ID is provided along with colony number in the case of iPSCs. All analyses were conducted using average linkage and Euclidean distance. a Clustering based on log2-transformed gene expression scores from 546 probe sets with coefficient of variation (CV) greater than 0.25 and conducted using average linkage and Euclidean distance. b Clustering based on log2-transformed gene expression scores corresponding to 26 pluripotency-related genes that are differentially expressed between fibroblasts and iPSC (>1.5 fold change, FDR < 0.05). Color bars represent log-2 transformed gene expression values for each panel

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