Table 1 HBPs differentially regulated in periodontal disease
From: In silico analyses of heparin binding proteins expression in human periodontal tissues
Protein name | Protien abbreviation |
|---|---|
Up regulated HBPs | |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 | ADAMTS1 |
Arginase, liver | ARG1 |
Chemokine (C–C motif) ligand 19 | CCL19 |
Complement factor H | CFH |
Chemokine (C–X–C motif) ligand 1 | CXCL1 |
Chemokine (C–X–C motif) ligand 12 | CXCL12 |
Chemokine (C–X–C motif) ligand 13 (B cell chemoattractant) | CXCL13 |
Chemokine (C–X–C motif) ligand 2 | CXCL2 |
Chemokine (C–X–C motif) ligand 6 (granulocyte chemotactic protein 2) | CXCL6 |
Fibronectin 1 | FN1 |
Heparin-binding EGF-like growth factor | HBEGF |
Insulin-like growth factor 2 mRNA binding protein 3 | IGFBP6 |
Interleukin 10 | IL10 |
Interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | IL12B |
Interleukin 6 (interferon, beta 2) | IL6 |
Interleukin 8 | IL8 |
Inhibin, beta A (activin A, activin AB alpha polypeptide) | INHBA |
Lactotransferrin | LTF |
Matrix metallopeptidase 2 (gelatinase A, 72 kDa gelatinase, 72 kDa type IV collagenase) | MMP2 |
Matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase) | MMP9 |
Plasminogen activator, urokinase | PLAU |
Serpine peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | SERPINE1 |
Tenascin C (hexabrachion) | TNC |
Tumour necrosis factor | TNF |
Vascular endothelial growth factor | VEGFA |
Down regulated HBPs | |
Amyloid P component, serum | APCS |
Chemokine (C–C motif) ligand 2 | CCL2 |
Chemokine (C–C motif) ligand 3 | CCL3 |
Chemokine (C–C motif) ligand 4 | CCL4 |
Chemokine (C–C motif) ligand 5 | CCL5 |
CD36 molecule | CD36 |
Complement factor B | CFB |
Connective tissue growth factor | CTGF |
Chemokine (C–X–C motif) ligand 10 | CXCL10 |
Fibroblast growth factor 2 (basic) | FGF2 |
Fibroblast growth factor receptor 3 | FGFR3 |
Fibronectin | FN1 |
Glycoprotein (transmembrane) | GPNMB |
Interferon, gamma | IFNG |
Insulin-like growth factor binding protein 2, 36 kDa | IGFBP2 |
Interleukin 2 | IL2 |
Interleukin 6 (interferon, beta 2) | IL6 |
Interleukin 8 | IL8 |
Matrix metallopeptidase 14 (membrane-inserted) | MMP14 |
Urokinase | PLAU |
Thyroglobulin | TG |
Thrombospondin 1 | THBS1 |
Tumour necrosis factor | TNF |