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Table 3 Comparison of biochemical parameters among fractionated extract of A. africanus treated groups, at doses of 300 and 600 mg/kg body weight/day, and the control mice

From: Toxicological study of the butanol fractionated root extract of Asparagus africanus Lam., on some blood parameter and histopathology of liver and kidney in mice

Biochemical parameters

Control

300 mg/kg bwt

600 mg/kg bwt

Value

% of mean difference

P value

Value

% of mean difference

P value

AST

(IU/L)

208.17 ± 44.84

208.17 ± 51.63

0

1.00

261.20 ± 32.38

17.06

0.49

ALP

(IU/L)

74.00 ± 29.46

75.00 ± 10.25

1.33

0.34

76.32 ± 31.45

3.03

0.25

ALT

(IU/L)

107.50 ± 34.88

84.67 ± 9.64

−21.24

0.47

82.80 ± 13.41

−25

0.40

Urea

(mg/dL)

49.00 ± 2.91

52.33 ± 6.92

6.36

0.60

46.40 ± 1.33

−6.47

0.62

Creatnine (mg/dL)

0.88 ± 0.11

0.83 ± 0.11

−5.68

0.75

1.24 ± 0.16

26.67

0.08

  1. Data are expressed as Mean ± SEM, n = 12