Skip to main content

Table 2 CSF profiles and imaging findings

From: Normocellular CSF in herpes simplex encephalitis

CSF Profile

CSF pleocytosis group (WBC > 5cells/mm3)

Normocellular CSF group (WBC ≤ 5cells/mm3)

Days of CSF examination after neurological onset

Day 0—1: 5 (29.4 %)

Day 2—10: 12 (70.6 %)

Day 0—1: 1 (16.7 %)

Day 2—10: 5 (83.3 %)

CSF protein

0–60 mg/dl: 1 (6.3 %)

61–100 mg/dl: 7 (43.8 %)

>100 mg/dl: 8 (50 %)

Not available: 1

0–60 mg/dl: 2 (33.3 %)

61–100 mg/dl: 4 (66.7 %)

>100 mg/dl: 0

CSF glucose

<30 mg/dl: 1 (6.3 %)

31–60 mg/dl: 7 (43.8 %)

>60 mg/dl: 8 (50 %)

Not available: 1

<30 mg/dl: 0

31–60 mg/dl 1 (16.7 %)

>60 mg/dl: 5 (83.3 %)

Average CSF viral load

12,200 copies/ml (39–11,755,813 copies/ml) (11 cases available: 6 had qualitative test)

3027 copies/ml

(59–5970 copies/ml)

(4 cases available: 3 had qualitative test)

Brain imaging findings

16 available records

6 available records

 Predominant temporal lobe lesions

5 (29.4 %)

1 (16.7 %)

 Fronto-temporal lesions

4 (23.5 %)

1 (16.7 %)

 Other cortical and subcortical lesions (non fronto-temporal)a

3 (18.8 %)

0

 Fronto-temporal and thalamic lesionsa

3 (18.8 %)

0

 Normal or Miscellaneousb

0

2 (33.3 %)

 Normal CT (MRI not performed)

1 (5.9 %)

2 (33.3 %)

  1. aTwo of the patients (a non fronto-temporal lesion and one with fronto-temporal and thalamic lesions) also had vasculitis, visualized using magnetic resonance angiography
  2. bMiscellaneous refers to non-specific lesions such as non-specific white matter changes, aging brain etc