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Table 4 Coded, physician-defined differences between NAFLD and NASH

From: Awareness of nonalcoholic steatohepatitis and associated practice patterns of primary care physicians and specialists

Coded responses

PCPs

n = 152

Specialists

n = 150

P

Generalized differences (NET)

57 (38)

10 (7)

<0.001

 NASH is more severe than NAFLD

33 (22)

7 (5)

<0.001

 General differences in fat deposition

10 (7)

1 (1)

0.005

 NASH characterized by a rise in liver enzymes

19 (13)

2 (1)

<0.001

Thought they were the same

13 (9)

0 (0)

<0.001

NASH associated with excess alcohol intake

8 (5)

3 (2)

0.081

NAFLD involves no inflammation of the liver

45 (30)

101 (67)

<0.001

There is no rise in liver function tests associated with NAFLD, but there is with NASH

15 (10)

11 (7)

0.432

Both NASH and NAFLD can be associated with a rise in liver function tests

7 (5)

5 (3)

0.199

Increase of fat in the liver associated with both

32 (21)

41 (27)

0.202

Histologic features (NET)

24 (16)

77 (51)

<0.001

 NASH is diagnosed via a liver biopsy

5 (3)

21 (14)

<0.001

 Presence of ballooning indicates NASH

0 (0)

10 (7)

<0.001

 Differences in levels of fibrosis/scarring/cirrhosis indicates NASH

19 (13)

45 (30)

<0.001

NASH involves damage to the liver

21 (14)

17 (11)

0.515

Not sure of the differences

50 (33)

2 (1)

<0.001

  1. Numbers indicate the number of respondents (percentage of total respondents)