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Table 2 Change in anxiety during treatment (mITT population)

From: Adherence to interferon β-1a therapy using an electronic self-injector in multiple sclerosis: a multicentre, single-arm, observational, phase IV study

Measure

Baseline

Week 12

Week 24

Hospital anxiety and depression scale

 Anxiety subscale score

(range 0–21)

7.0 ± 4.1

5.8 ± 4.3*

5.9 ± 4.1*

State–trait anxiety inventory

 State anxiety subscale

(range 20–80)

40.4 ± 12.3

35.9 ± 12.7*

36.6 ± 12.9*

 Trait anxiety subscale

(range 20–80)

38.8 ± 10.9

36.7 ± 12.1*

37.6 ± 12.1

  1. * p < 0.005 by comparison to baseline, as calculated by a paired t-test
  2. mITT modified intent-to-treat