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Table 6 Effects of ethanol extract of S. jambos and indomethacin on carrageenan-induced oedema paw volume in wistar rats

From: HPLC profiling, antioxidant and in vivo anti-inflammatory activity of the ethanol extract of Syzygium jambos available in Bangladesh

Treatment

Dose

Right hind paw volume (% inhibition)

(mg/kg)

1 h

2 h

3 h

4 h

5 h

Vehicle

10 (ml/kg)

0.98 ± 0.12

1.07 ± 0.16

1.26 ± 0.21

1.35 ± 0.23

1.43 ± 0.25

Indomethacin

10

0.46 ± 0.15 (53.06)*

0.47 ± 0.19 (56.07)*

0.53 ± 0.17 (57.94)*

0.54 ± 0.16 (60.00)*

0.53 ± 0.18 (62.94)**

S. jambos

200

0.74 ± 0.13 (24.49)*

0.69 ± 0.14 (35.51)*

0.74 ± 0.18 (41.27)**

0.75 ± 0.15 (44.44)*

0.73 ± 0.17 (48.95)**

S. jambos

400

0.65 ± 0.15 (33.67)*

0.58 ± 0.17 (45.79)**

0.59 ± 0.19 (53.18)**

0.61 ± 0.18 (54.82)*

0.60 ± 0.17 (58.04)**

  1. Each value is presented as the mean ± SEM (n = 5)
  2. * P < 0.05 compared with control group (Dunnett’s test)
  3. ** P < 0.01 compared with control group (Dunnett’s test)