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Table 7 Effect of ethanol extract of S. jambos and indomethacin on histamine-induced oedema paw volume in wistar rats

From: HPLC profiling, antioxidant and in vivo anti-inflammatory activity of the ethanol extract of Syzygium jambos available in Bangladesh

Treatment

Dose

Right hind paw volume (% Inhibition)

(mg/kg)

1 h

2 h

3 h

4 h

5 h

Vehicle

10 (ml/kg)

1.10 ± 0.15

1.25 ± 0.19

1.34 ± 0.18

1.40 ± 0.22

1.52 ± 0.21

Indomethacin

10

0.56 ± 0.14 (49.09)*

0.57 ± 0.16 (54.40)*

0.58 ± 0.15 (56.72)*

0.53 ± 0.19 (62.14)**

0.52 ± 0.13 (65.79)**

S. jambos

200

0.76 ± 0.11 (30.91)

0.80 ± 0.17 (36.00)**

0.86 ± 0.23 (35.82)*

0.84 ± 0.15 (40.00)**

0.82 ± 0.18 (46.05)**

S. jambos

400

0.67 ± 0.13 (39.09)

0.69 ± 0.14 (44.80)*

0.72 ± 0.16 (46.27)*

0.74 ± 0.14 (47.14)*

0.70 ± 0.19 (53.95)**

  1. Each value is presented as the mean ± SEM (n = 5)
  2. * P < 0.05 compared with control group (Dunnett’s test)
  3. ** P < 0.01 compared with control group (Dunnett’s test)