Table 4 SuperPaths overrepresented among genes upregulated in the trophectoderm by CSF2

Inhibitory actions of lipoxins on superoxide production in neutrophils (score = 25.39)—9 genes

 FOS, GNG12, GNG2, GNGT2, JUN, PLD1, NFKBIA, PIK3CG, PREX1

Translation regulation by alpha-1 adrenergic receptors (score = 19.66)—8 genes

 ADRA1A, FOS, GNG12, GNG2, GNGT2, JUN, PLD1, PRKCE

Hypertrophy model (score = 18.66)—5 genes

 ANKRD1, ATF3, CYR61, HBEGF, IFNG

Apoptotic pathways in synovial fibroblasts (score = 16.29)—22 genes

 ANK1, ARHGDIB, CACNA2D1, CTGF, FOS, GNG12, GNG2, GNGT2, HBEGF, ITGB3, JUN, KITLG, KLF10, MAP3K8, NFKBIA, NRP1, PLD1, PPARA, PPP1R14A, PRKCE, RHOB, ZAP70

G-protein signaling ras family gtpases in kinase cascades (score = 15.90) 8 genes

 CYR61, FOS, FOSB, JUN, LDLR, NFKBIA, PRKCE, SIPA1

Toll comparative pathway (score = 15.54) 8 genes

 ATF3, FOS, FOSB, GNG2, IFNG, IL1RAP, JUN, NFKBIA

ERK signaling (score = 15.12) 29 genes

 ARHGDIB, ATF3, CACNA2D1, CAPN11, CTGF, DUSP1, FOS, FOSB, GNG12, GNG2, GNGT2, HBEGF, IL17A, ITGB3, JUN, KITLG, KLF10, MAP3K8, NFKBIA, NRP1, PIK3CG, PLD1, PPP1R14A, PRKCE, RHOB, SMAD9, SPP1, TNFRSF8, ZAP70

Osteopontin-mediated events (score = 15.0)—5 genes

 FOS, ITGB3, JUN, NFKBIA, SPP1

ATF-2 transcription factor network (score = 14.65)—6 genes

 ATF3, DUSP1, DUSP5, FOS, IFNG, JUN

Angiotensin activation of ERK (score = 14.51)—11 genes

 FOS, GNG12, GNG2, GNGT2, HBEGF, KITLG, ITGB3, JUN, PIK3CG, PRKCE, ZAP70

LPA receptor mediated events (score = 13.79)—6 genes

 FOS, GNG2, HBEGF, JUN, NFKBIA, PRKCE