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Table 2 Personal and clinical characteristics of patients carrying or not BRCA1/2 mutations

From: Clinical and pathological features of BRCA1/2 tumors in a sample of high-risk Moroccan breast cancer patients

Variable

BRCA1/2+

BRCA1/2−

p value

Family history

   

 No

1(9.1 %)

5 (17.2 %)

0.66

 Yes

10 (90.9 %)

24 (82.8 %)

 

Mean age at diagnosis (years)

37.90 (SD = 6.67)

44.48 (SD = 9.74)

0.05

Mean age at menarche (years)

13.08 (SD = 1.60)

14.24 (SD = 1.62)

0.05

Mean age at first delivery (years)

25.15 (SD = 5.76)

25.57 (SD = 6.60)

0.88

Mean age at menopause (years)

47.50 (SD = 0.70)

48.66 (SD = 5.60)

0.79

Breastfeeding

 No

4 (36.4 %)

12 (41.4 %)

1.00

 Yes

7 (63.6 %)

17 (58.6 %)

 

Average duration of breastfeeding (months)

8.71 (SD = 5.40)

19.35 (SD = 12.92)

0.05

Oral contraceptive use

 No

6 (54.5 %)

11 (37.9 %)

0.48

 Yes

5 (45.5 %)

18 (62.1 %)

 

Parity

 Nulliparous

4 (36.4 %)

10 (34.5 %)

1.00

 Parous

7 (63.6 %)

19 (65.5 %)

 

Tumor localization

 Unilateral

10 (90.9 %)

28 (96.6 %)

1.00

 Bilateral

1 (9.1 %)

1 (3.4 %)

 
  1. Values in Italic are statistically significant (p value ≤ 0.05)