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Table 1 List of contraindicated drug combinations and potential risk

From: Potential drug–drug interactions among elderly patients admitted to medical ward of Ayder Referral Hospital, Northern Ethiopia: a cross sectional study

Drug combinations

Number of patients

Documentationa

Potential risks

Clarithromycin simvastatin

3

Good

Increased risk of myopathy or rhabdomyolysis

Clarithromycin ciprofloxacin

1

Fair

Increased risk of QT interval prolongation

Total

4

  
  1. a Documentation based on available studies or reports: good, studies strongly suggest that the interaction exists except proof of well-controlled studies; fair, available evidences are poor, but the interaction is suspected on the basis of pharmacologic considerations; or, evidences are good for an interaction of pharmacologically similar drug [24]