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Table 6 TSQM domain and global scores: ANCOVA analyses

From: The real-world patient experience of fingolimod and dimethyl fumarate for multiple sclerosis

TSQM scale

ANOVA

ANCOVAa

LS meanb

95 % CI

p valuec

LS meanb

95 % CI

p valuec

Effectiveness

 CF

65.2

59.9, 70.5

 

65.0

59.6, 70.5

 

 CDMF

66.1

62.5, 69.8

 

66.2

62.5, 70.0

 

 Difference

−0.9

−7.4, 5.5

0.776

−1.2

−7.9, 5.4

0.720

Convenience

 CF

94.4

90.6, 98.3

 

94.8

90.9, 98.6

 

 CDMF

86.8

84.2, 89.4

 

86.7

84.1, 89.3

 

 Difference

7.6

3.0, 12.3

0.001

8.1

3.4, 12.8

<0.001

Side effects

 CF

91.6

85.6, 97.5

 

91.3

85.3, 97.3

 

 CDMF

81.6

77.8, 85.5

 

81.8

77.9, 85.6

 

 Difference

10.0

2.8, 17.1

0.007

9.5

2.3, 16.8

0.010

Global

 CF

76.0

70.2, 81.8

 

75.5

69.7, 81.4

 

 CDMF

68.8

64.8, 72.8

 

69.0

65.0, 73.0

 

 Difference

7.2

0.1, 14.2

0.047

6.5

−0.6, 13.7

0.076

  1. aCovariates: age (continuous), gender (male/female), and Total MSRS-R score (continuous)
  2. bHigher scores indicate higher treatment satisfaction (greater perceived effectiveness, greater satisfaction, fewer/less severe side effects, greater global satisfaction)
  3. cp values are provided as descriptive statistics to assess the degree of difference between each LS mean estimate and zero