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Table 3 Factors associated with PCS Scores across treatment phases among sputum smear positive PTB patients in Mbale regional referral hospital

From: Does health-related quality of life among adults with pulmonary tuberculosis improve across the treatment period? A hospital-based cross sectional study in Mbale Region, Eastern Uganda

Factors

Pretreatment phase

Intensive phase

Continuation phase

Unadjusted β (p value)

Adjusted β (p value)

Unadjusted β (p value)

Adjusted β (p value)

Unadjusted β (p value)

Adjusted β (p value)

Age

−0.56 (0.003)

−0.13 (0.498)

−0.24 (0.101)

0.20 (0.203)

−0.43 (0.013)

−0.43 (0.013)

Sex

 Male

Ref

 

Ref

 

Ref

 

 Female

−4.06 (0.414)

 

3.58 (0.325)

 

−1.38 (0.765)

 

Marital status

 Married

Ref

Ref

Ref

Ref

Ref

 

 Separated

−6.40 (0.276)

−3.23 (0.551)

−4.87 (0.213)

−6.61 (0.092)

−3.64 (0.516)

 

 Single

14.11 (0.009)

−1.93 (0.740)

14.97 (0.002)

11.94 (0.028)

4.26 (0.430)

 

Family size

 0–3

Ref

 

Ref

 

Ref

 

 4+

7.15 (0.126)

 

4.01 (0.314)

 

3.93 (0.500)

 

Education level

 None or primary

Ref

 

Ref

 

Ref

 

 Secondary and above

3.95 (0.397)

 

2.99 (0.387)

 

5.32 (0.236)

 

Religion

 Christian

Ref

 

Ref

 

Ref

 

 Non-christian

6.19 (0.264)

 

−0.38 (0.914)

 

0.80 (0.864)

 

HIV co-infection

 Yes

Ref

Ref

Ref

Ref

 

Ref

 No

1.25 (0.790)

−3.68 (0.352)

2.35 (0.516)

−3.28 (0.307)

−1.66 (0.715)

−2.14 (0.623)

Alcohol consumption

 Yes

Ref

Ref

Ref

 

Ref

 

 No

−6.84 (0.167)

−2.42 (0.588)

−2.26 (0.520)

 

0.58 (0.902)

 

Employment

 No

Ref

Ref

Ref

 

Ref

 

 Yes

−16.58 (0.002)

1.19 (0.855)

−4.28 (0.212)

−4.20 (0.191)

4.11 (0.382)

 

Occupation

 Formal

Ref

Ref

Ref

 

Ref

 

 Informal

−31.55 (<0.001)

−28.66 (<0.001)

−6.52 (0.074)

 

−8.99 (0.100)

 

SES tertiles

 Lowest

Ref

 

Ref

Ref

Ref

Ref

 Middle

1.62 (0.758)

 

0.98 (0.783)

3.16 (0.342)

13.11 (0.009)

12.78 (0.009)

 Highest

8.48 (0.181)

 

14.36 (0.008)

14.56 (0.007)

8.65 (0.131)

6.19 (0.248)

Residence

 Typical rural/village

Ref

Ref

Ref

 

Ref

 

 Trading center

10.06 (0.031)

4.24 (0.288)

−3.12 (0.366)

 

3.06 (0.507)

 

 Sputum grade

 1+

Ref

 

Ref

Ref

Ref

 

 2+

5.37 (0.411)

 

9.31 (0.048)

13.26 (0.004)

4.52 (0.467)

 

 3+

2.77 (0.643)

 

3.45 (0.434)

5.84 (0.152)

−3.71 (0.507)

 

Treatment strategy

 Community-based DOTS

Ref

 

Ref

 

Ref

 

 Facility-based DOTS

0.0185 (0.998)

 

2.72 (0.526)

 

1.86 (0.784)

 

Family disclosure

 No

Ref

Ref

Ref

 

Ref

 

 Yes

10.42 (0.024)

5.20 (0.222)

−0.60 (0.871)

 

4.60 (0.382)

 

Family support

 Yes

Ref

 

Ref

 

Ref

 

 No

1.33 (0.805)

 

2.88 (0.513)

 

−5.06 (0.399)

 

Community aware

 Yes

Ref

 

Ref

 

Ref

 

 No

26.49 (0.056)

 

3.31 (0.341)

 

2.11 (0.650)

 

Community attitude

 Supportive

Ref

Ref

Ref

 

Ref

Ref

 Not supportive

−2.21 (0.777)

−5.29 (0.443)

2.77 (0.425)

 

2.11 (0.650)

2.17 (0.623)

Social support group

 Yes

Ref

 

Ref

 

Ref

 

 No

1.74 (0.848)

 

−1.33 (0.794)

 

1.79 (0.759)