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Table 1 Prevalence of M. tuberculosis among presumptive TB patients referred to DMRH using Gene Xpert MTB/RIF assay, 2015

From: Rifampicin-resistance pattern of Mycobacterium tuberculosis and associated factors among presumptive tuberculosis patients referred to Debre Markos Referral Hospital, Ethiopia: a cross-sectional study

Characters

M. tuberculosis

Total

N (%)

P value

Detected

N (%)

Not detected

N (%)

Age, years

 ≤10

9 (23.7)

29 (76.3)

38 (7.5)

0.017

 11–17

7 (29.2)

17 (70.8)

24 (4.8)

 

 18–30

46 (34.3)

88 (65.7)

134 (26.7)

 

 31–40

25 (18.7)

109 (81.3)

134 (26.5)

 

 41–50

15 (15.1)

82 (84.5)

97 (19.2)

 

 51–60

9 (18)

41 (82)

50 (9.9)

 

 61–95

6 (21.4)

22 (79.6)

28 (5.5)

 

Sex

 Male

74 (27.9)

191 (72.1)

265 (52.4)

0.008

 Female

43 (17.9)

197 (82.1)

240 (47.6)

 

Residence

 Urban

57 (20.2)

225 (79.8)

282 (55.7)

0.007

 Rural

60 (26.9)

163 (73.1)

223 (44.3)

 

HIV infection

 Positive

30 (16.6)

153 (83.4)

183 (36)

0.008

 Negative

87 (26.9)

235 (73.1)

322 (64)

 

Reason for diagnosis

 Presumptive TB

48 (15.1)

269 (84.8)

317 (62.8)

<0.001

 Presumptive DR TB

69 (36.7)

119 (63.3)

188 (37.2)

 

Treatment history with anti-TB drugs

 Previously treated

41 (31.6)

91 (68.9)

132 (26.2)

0.013

 Previously untreated

76 (20.4)

297 (79.6)

372 (73.8)

 

Presumptive DRTB

 New

28 (45.2)

34 (54.8)

62 (32)

0.024

 Relapse

26 (25.7)

75 (74.3)

101 (52.1)

 

 Failure

14 (92.3)

12 (7.7)

26 (13.4)

 

 Lost to follow-up

0

1

1 (0.5)

 

 MDR-contact

1 (25)

3 (75)

4 (2.1)

 

Site of presumptive TB

 Pulmonary

64 (19.8)

259 (80.2)

323 (64)

0.013

 Extra-pulmonary

53 (29.1)

129 (70.9)

182 (36)

 

Type of specimen

 Respiratory (sputum)

64 (19.8)

259 (80.2)

323 (64)

0.007

 Non-respiratory

53 (29.1)

129 (70.9)

182 (36)

 

Type of non-respiratory specimen

 Pus

46 (35.1)

85 (64.9)

131 (26)

 

 Peritoneal fluid

2 (11.8)

15 (88.2)

17 (3.4)

 

 Lymph node aspirate

1 (7.1)

13 (92.9)

14 (2.8)

 

 Pleural fluid

3 (23.1)

10 (76.9)

13 (2.6)

 

 Other

1 (14.3)

6 (83.7)

7 (1.2)

 

Total

117 (23.2)

388 (76.8%)

505 (100)

 
  1. MTB M. tuberculosis, DR TB drug resistant tuberculosis