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Table 1 Serial CSF data from lumbar puncture and ventricular drain

From: Immunological diagnosis as an adjunctive tool for an early diagnosis of tuberculous meningitis of an immune competent child in a low tuberculosis endemic country: a case report

CSF data

Day 1 CSF-LP

Day 9 CSF-LP

Day 14 CSF- LP

Day 18 CSF- LP

Day 18 CSF-VD

Day 21 CSF-LP

Day 21 CSF-VD

Day 27 CSF-LP

Day 27 CSF-VD

Day 40 CSF-LP

Day 52 CSF-LP

Appearance

Clear

Clear

Clear

Clear

Clear

Clear

Clear

Clear

Clear

Clear

Clear

WBC count/µL

372

919

321

139

62

718

21

628

120

1.025

291

Neutrophil %

4%

1.3%

9%

17%

 

11%

 

6%

 

4%

20%

Lymphocyte %

90%

98%

81%

74%

61%

78%

78%

90%

84%

91%

72%

Glucose mg/dL

13

15

13

16

45

16

58

9

41

18

18

Protein level mg/dL

1.317

1.993

3.367

2.083

801

14.444

1.746

>6.000

1.881

2.097

2.512

Lactic acid mg/dL

64.9

 

65.8

56,8

32.4

56.8

25.2

45.1

45.1

44.1

36.9

ADA (U/L)

18.31

 

9.18

5.02

   

10.24

 

4.05

2.89

Direct gram stain

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

PCR M. tuberculosis

Neg

Pos a

        

Neg

Culture M. tuberculosis

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Bacterioscopic exam for AFB

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

Neg

  1. LP lumbar puncture, VD ventricular drain, AFB acid-fast bacilli
  2. aIn house nested PCR, while the GeneXpert MTB/RIF assay was negative