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Table 1 Baseline parameters

From: RANTES levels in peripheral blood, CSF and contused brain tissue as a marker for outcome in traumatic brain injury (TBI) patients

Parameters

Severe head injury (n = 30)

Moderate/mild head injury (n = 30)

Healthy control (n = 15)

p value

Bonferroni’s correction

Age

37.5 ± 13.53

36.6 ± 11.49

30.8 ± 6.64

0.17

Sexa

 Male

25 (83.33)

28 (93.33)

12 (80.0)

0.40

 Female

5 (16.67)

2 (6.67)

3 (20.0)

Mode of injurya

 RTA

24 (80.0)

20 (66.67)

0.56

 

 Fall

4 (13.33)

7 (23.33)

 Miscellaneous

2 (6.67)

3 (10.0)

ICU Length of stayb

4 (0–25)

1 (0–12)

0.0007

 

Hospital length of stayb

6.5 (1–181)

3 (1–61)

0.14

 

Systolic BP

123.9 ± 32.10

124.5 ± 18.26

0.93

 

Time elapsed from injury to sampling (h)b

9 (1–24)

6 (1–20)

0.11

 

Urea (meq/l)

29.5 ± 11.18

27.3 ± 9.77

26.3 ± 5.96

0.52

 

Creatinine (meq/l)

0.9 ± 0.3

0.8 ± 0.2

0.7 ± 0.22

0.22

 

Sodium (meq/l)

140.7 ± 4.8

140.0 ± 4.04

141.2 ± 2.85

0.63

 

Potassium (meq/l)

3.9 ± 0.68

3.8 ± 0.56

4.4 ± 0.42

0.01

SHI versus HC 0.04

MHI versus HC 0.01

Hemoglobin (g/dl)

12.1 ± 3.49

11.6 ± 1.76

13.4 ± 1.69

0.13

 

Total leukocyte count (x/cu mm)b

15,600 (4400–25,700)

10,500 (850–24,800)

6800 (4300–10,200)

0.0001

 

Platelet (/cu mm)b

153 (56–338)

150 (67–303)

202 (120–340)

0.10

 

Prothrombin time (s)

16.5 ± 4.06

15.2 ± 1.99

15.2 ± 1.84

0.19

 

Activated partial thrombin time (s)

29.8 ± 7.51

27.7 ± 4.06

31.5 ± 6.24

0.13

 

INR

1.3 ± 0.4

1.2 ± 0.1

1.1 ± 0.01

0.12

 

Emergency surgery

 Yes

16

10

  

 No

14

20

Sepsis

 Yes

9 (30)

4 (13.3)

   

 No

21 (70)

26 (86.7)

Outcomea

Alive

14 (46.67)

26 (89.66)

0.001

 

Dead

16 (53.33)

3 (10.34)

Glasgow outcome score (GOS)a

 Good recovery

0 (0.00)

7 (25)

 

<0.001

 

 Moderate disability

5 (17.86)

18 (64.29)

 Severe disability

6 (21.43)

0 (0.00)

 Persistent vegetative

0

0 (0.00)

 Death

16 (57.14)

3 (10.71)

  1. One-way ANOVA applied; data represented as mean ± SD
  2. SHI severe head injury, MHI moderate and mild head injury, HC healthy control
  3. aFrequency (%)
  4. bMedian (min–max)