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Table 5 Age-adjusted Incidence rate ratios for cytophilic IgG with malaria incidence from low to the end of high transmission season

From: Antibody responses to P. falciparum blood stage antigens and incidence of clinical malaria in children living in endemic area in Burkina Faso

Antibodies/antigen

Parasitemia > 0

Parasitemia > 2500

Parasitemia > 5000

Age adjusted (95% CI)

p

Age adjusted (95% CI)

p

Age adjusted (95% CI)

p*

IgG1

MSP3

0.94 (0.897, 0.989)

0.016

0.93 (0.872, 0.988)

0.02

0.93 (0.874, 0.995)

0.034

 

MSP2a

0.99 (0.956, 1.031)

0.7

0.98 (0.936, 1.029)

0.44

0.97 (0.919, 1.014)

0.16

 

MSP2b

1.00 (0.959, 1.037)

0.90

0.98 (0.936, 1.033)

0.5

0.98 (0.932, 1.032)

0.45

 

GLURP-R0

0.93 (0.892, 0.965)

0.0002

0.90 (0.851, 0.942)

0.00002

0.89 (0.845, 0.939)

0.00002

 

GLURP-R2

0.96 (0.932, 0.982)

0.001

0.94 (0.914, 0.976)

0.0007

0.94 (0.912, 0.977)

0.001

IgG3

MSP3

0.97 (0.940, 0.996)

0.024

0.95 (0.913, 0.983)

0.004

0.94 (0.908, 0.981)

0.003

 

MSP2a

0.99 (0.960, 1.020)

0.49

0.97 (0.934, 1.008)

0.12

0.97 (0.929, 1.005)

0.091

 

MSP2b

0.98 (0.948, 1.005)

0.1

0.95 (0.911, 0.981)

0.003

0.94 (0.903, 0.975)

0.0011

 

GLURP-R0

0.98 (0.942, 1.010)

0.16

0.96 (0.918, 1.003)

0.068

0.96 (0.913, 1.001)

0.056

 

GLURP-R2

0.96 (0.936, 0.982)

0.0007

0.94 (0.907, 0.966)

0.00003

0.93 (0.903, 0.964)

0.00003

  1. *  p ≤ 0.05 was considered as statistically significant