Table 2 In vitro antifungal susceptibility profile of various Candida species
From: Antifungal susceptibility and phenotypic virulence markers of Candida species isolated from Nepal
CLSI breakpoints (μg/ml) | Amphotericin B | Caspofungin | Fluconazole | Voriconazole | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
S | I | R | S | I | R | S | I | R | S | I | R | |
≤ 4 | 8–16 | ≥ 32 | ≤ 0.25 | 0.5 | ≥ 1 | ≤ 2 | 4 | ≥ 8 | ≤ 0.12 | 0.25–0.5 | ≥ 1 | |
C. albicans, n = 48 (%) | 47 (97.9) | 0 (0) | 1 (2.1) | 41 (85.4) | 4 (8.3) | 3 (6.3) | 11 (23) | 14 (29) | 23 (48) | 37 (77) | 11 (23) | 0 (0) |
C. tropicalis, n = 11 (%) | 0 (0) | 11 (100) | 0 (0) | 11 (100) | 0 0 | 0 0 | 4 (36.4) | 1 (9) | 6 (54.6) | 0 0 | 9 (81.8) | 0 (18.2) |
C. glabrata, n = 9 (%) | 0 (0) | 9 (100) | 0 (0) | 9 (100) | 0 0 | 0 0 | 6 (66.7) | 1 (11.1) | 2 (22.2) | 0 0 | 8 (88.9) | 1 (11.1) |
C. krusei, n = 3 (%) | 0 0 | 2 (66.7) | 1 (33.3) | 2 (66.7) | 1 (33.3) | 0 (0) | 1 (33.3) | 0 (0) | 2 (66.7) | 0 0 | 2 (66.7) | 1 (33.3) |