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Table 1 Second-line drug susceptibility results for patient 1 and 2

From: Extensively drug resistant tuberculosis in Mali: a case report

 

Sample collection date

MTBDRplus

rpoB

MTBDRplus

katG

MTBDRplus

inhA

MTBDRsld

gyrA

MTBDRsld

rrs

MTBDRsld

eis

Patient 1

May 2016

MUT1

(D516V)

MUT1

(S315T)

MUT3B

(T8A)

MUT3C

(D94G)

MUT1

(A1401G)

WT

Patient 2

May 2016

MUT1

(D516V)

WT

MUT3B

(T8A)

MUT3C

(D94G)

MUT1

(A1401G)

WT

Patient 3

Feb 2017

MUT1

(D516V)

MUT1

(S315T)

MUT3B

(T8A)

MUT3C

MUT3B

(D94G)

MUT1

(A1401G)

WT

  1. “Point mutations in: the rpoB gene confer resistance to rifampicin; katG gene and in the inhA gene promoter confer resistance to isoniazid; gyrA and gyrB confer resistance to fluoroquinolones; and rrs confers resistance to kanamycin” WT = wild type (no resistance). MUT = mutation in position 1, position 3B, or position 3C of the gene, with specific mutation indicated