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Table 3 Effect of chronic oral administration of G. stenophylla root extract on some serum biochemical parameters in mice

From: Toxicological investigation of acute and chronic treatment with Gnidia stenophylla Gilg root extract on some blood parameters and histopathology of spleen, liver and kidney in mice

Biochemical parameters

Control

Treatment groups (mg/kg body weight/day)

400

800

Total protein (g/dL)

2.03 ± 0.05

1.96 ± 0.28 (0.842)

1.84 ± 0.21 (0.572)

ALP (IU/L)

50.00 ± 6.14

32.01 ± 15.72 (0.496)

47.00 ± 11.92 (0.909)

ALT (IU/L)

23.75 ± 0.85

22.60 ± 3.06 (0.777)

19.00 ± 3.05 (0.255)

AST (IU/L)

73.75 ± 12.66

87.80 ± 12.6 (0.520)

48.73 ± 0.12 (0.769)

Urea (mg/dL)

50.00 ± 3.42

38.80 ± 8.42 (0.281)

43.20 ± 6.44 (0.506)

Creatinine (mg/dL)

0.23 ± 0.03

0.30 ± 0.03 (0.144)

0.28 ± 0.04 (0.273)

  1. Values are given as mean ± S.E.M. n = 10. The figures under brackets indicate the calculated P values of the treatment groups as compared to the control