Table 1 Characteristics of the 301 recruited TB patients and differences in treatment outcomes
From: Predictors of therapy failure in newly diagnosed pulmonary tuberculosis cases in Beira, Mozambique
Characteristics | Study population n. 301 | Treatment | p-value | |
|---|---|---|---|---|
Failure n. 62 | Success n. 239 | |||
Average age (years) | 31 (12.5) | 33.3 (12.8) | 30.4 (12.1) | 0.84 |
Female n. (%) | 98 (32.6) | 24 (24.5) | 74 (75.5) | < 0.0001 |
No education | 145 (48.2) | 41 (28.3) | 104 (71.7) | < 0.0001 |
Employed | 187 (62.0) | 13 (6.9) | 174 (93.1) | < 0.0001 |
Monthly income ≤ 50 dollars | 218 (72.4) | 49 (22.5) | 169 (77.5) | < 0.0001 |
Lifestyles and behaviours | ||||
Current smoking | 25 (8.3) | 17 (68.0) | 8 (32.0) | < 0.0001 |
Alcohol use | 38 (12.6) | 21 (55.3) | 17 (7.1) | <0.0001 |
Sexual partner/s | < 0.0001 | |||
No | 110 (36.5) | 24 (21.8) | 86 (78.2) | < 0.0001 |
Yes | 184 (61.1) | 35 (56.4) | 149 (62.3) | |
Medical history and examination | ||||
Low BMI (< 18) | 169 (56.0) | 45 (26.6) | 124 (73.4) | < 0.0001 |
HIV positive | 131 (43.5) | 39 (37.4) | 92 (62.6) | < 0.0001 |
Antiretroviral treatment (ART) | 93 (30.9) | 18 (19.3) | 75 (80.7) | < 0.0001 |
Diabetes or IGT | 9 (3.0) | 6 (66.7) | 3 (33.3) | < 0.0001 |
Positive chest X-ray | 148 (49.2) | 9 (6.0) | 139 (94.0) | < 0.0001 |
Positive sputum examination | 246 (81.7) | 40 (16.3) | 206 (83.7) | < 0.0001 |
Positive GeneXpert | 56 (18.6) | 35 (62.5) | 21 (37.5) | < 0.0001 |
Symptoms before treatment | ||||
Cough | 296 (98.3) | 59 (20.4) | 237 (79.6) | <0.0001 |
Loss of weight | 261 (86.7) | 33 (12.6) | 228 (87.4) | < 0.0001 |
Astenia | 215 (71.4) | 25 (11.6) | 190 (88.4) | < 0.0001 |
Fever | 174 (57.8) | 24 (13.8) | 150 (86.2) | < 0.0001 |
Night sweat | 202 (67.1) | 26 (12.8) | 176 (87.2) | < 0.0001 |