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Table 2 Temperature, weight and packed cell volume of infected mice treated with crude extract of seed of C. molle in the 4 day suppressive test

From: Anti-plasmodial activities of Combretum molle (Combretaceae) [Zwoo] seed extract in Swiss albino mice

Animal Group

Packed cell volume

Body weight

Temperature

PCV-D0

PCV-D4

% change

BW0

BW4

% change

T0

T4

% change

Control

63.2 ± 0.97

49.6 ± 0.19

− 21.52

33.8 ± 0.63

28.6 ± 0.2

− 15.38

35.84 ± 0.54

36.7 ± 0.77

2.4

125

61.2 ± 0.78

51.6 ± 0.67

− 15.7b2

36.4 ± 0.47

33.6 ± 0.4a1

− 7.69

36.88 ± 0.19

37.02 ± 0.13

0.38a2

250

62.8 ± 0.09

51.2 ± 0.68

− 18.47b2

33.8 ± 0.96

32.9 ± 0.33a2

− 2.66

36.54 ± 0.16

36.62 ± 0.52

0.22a2

CQ

57 ± 0.68

53.5 ± 0.65

− 6.14

34.5 ± 0.41

32 ± 0.16

− 7.24

37.6 ± 0.34

36.45 ± 0.45

− 3.05

  1. Data are expressed as mean ± SD; a compared to control, b to chloroquine (CQ) 10 mg/kg; 1 P < 0.05; 2 P < 0.01
  2. D0 pre-treatment value on day 0, D4 post-treatment value on day 4, −ve sign shows reduction, +ve sign shows an increment