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Table 1 Descriptive statistics of studied population

From: Cytokeratin 5/6 and cytokeratin 8/18 expression in triple negative breast cancers: clinicopathologic significance in South-Asian population

 

n (%)

Age (years)a

48.85 ± 11.49

Age groups (years)

 ≤ 30

5 (3.3)

 31–50

84 (56)

 > 50

61 (40.7)

Tumor size (unit)a

4.01 ± 1.99

Tumor stage

 T1

26 (17.3)

 T2

79 (52.7)

 T3/T4

45 (30)

Ki67 index (%)

46.89 ± 23.88

ki67 index groups (%)

 ≤ 15

17 (11.3)

 16–24

8 (5.3)

 25–44

45 (30)

 > 44

80 (53.3)

Nodal status

 Positive

64 (42.7)

 Negative

86 (57.3)

Nodal stage

 No

88 (58.7)

 N1

30 (20)

 N2

13 (8.7)

 N3

19 (12.7)

Histological subtypes

 IDC

127 (84.7)

 Papillary

6 (4)

 Medullary

1 (0.7)

 Metaplastic

14 (9.3)

 Mixed

2 (1.3)

Tumor grade

 Grade-I

1 (0.7)

 Grade-II

19 (12.7)

 Grade-III

130 (86.7)

Lymphocytic infiltration

 Absent

15 (10)

 Moderate

110 (73.3)

 Severe

25 (16.7)

Lymphovascular invasion

 Present

36 (24)

 Absent

114 (76)

Dermal lymphatic invasion

 Present

10 (6.7)

 Absent

140 (93.3)

Type of surgery

 Modified radical mastectomy

94 (62.7)

 Simple mastectomy with sentinel lymph node dissection

42 (28)

 Wide local excision

14 (9.3)

Necrosis

 Absent

21 (14)

 Moderate

90 (60)

 Severe

39 (26)

Fibrosis

 Mild

42 (28)

 Moderate

88 (58.7)

 Severe

20 (13.3)

Insitu component

 Present

58 (38.7)

 Absent

92 (61.3)

Pagetoid spread

 Present

2 (1.3)

 Absent

148 (98.7)

Perinodal extension

 Present

30 (20)

 Absent

120 (80)

Adjuvant chemotherapy (n = 101)

 Yes

98 (97)

 No

3 (3)

Adjuvant radiotherapy (n = 101)

 Yes

69 (68.3)

 No

32 (31.7)

Reoccurrence (n = 101)

 Yes

18 (17.8)

 No

83 (82.2)

  1. aMean ± SD