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Table 2 Multivariable analysis of Weibull PH model for newly diagnosed T2DM patients in St. Paul’s Hospital, AA, from January 2008 to April 2017

From: Incidence and predictors of chronic kidney diseases among type 2 diabetes mellitus patients at St. Paul’s Hospital, Addis Ababa, Ethiopia

Variables

Category

CKD status

Crude HR [95% CI]

Adjusted HR [95% CI]

Censored

Event

Sex

Male

185

30

1

 

Female

188

32

0.94 (0.57, 1.54)

 

Age

   

1.07 (1.04, 1.09)

1.06 (1.03, 1.09)*

Diabetic retinopathy

Yes

357

47

1

1

No

16

15

0.11 (0.06, 0.2)

0.13 (0.07, 0.24)*

History of hypertension

No

174

26

1

 

Yes

199

36

1.18 (0.71, 1.95)

 

Hypertensive therapy

No

213

38

1

 

Yes

160

24

0.83 (0.5, 1.4)

 

Types of DM therapy

Insulin

85

16

1

 

Oral

288

46

0.96 (0.54, 1.7)

 

FBG(mg/dl)

   

0.99 (0.995, 1.002)

 

SBP (mmHg)

   

1.02 (1.01, 1.03)

 

DBP (mmHg)

   

1.03 (1.01, 1.05)

 

LDL cholesterol

< 100 mg/dl

221

40

1

 

≥ 100 mg/dl

113

22

1.02 (0.61, 1.72)

 

HDL cholesterol

< 40 mg/dl

155

45

1

1

≥ 40 mg/dl

179

17

0.35 (0.2, 0.62)

0.55 (0.31, 0.97)*

Total cholesterol

< 200 mg/dl

221

38

1

 

≥ 200 mg/dl

118

24

1.09 (0.65, 1.8)

 

Triglyceride

< 150 mg/dl

221

38

1

 
 

≥ 150 mg/dl

118

24

1.35 (0.81, 2.25)

 

BMI (kg/m2)

   

1.2 (1.1, 1.3)*

1.17 (1.1, 1.25)*

LR test χ2(6) = 96.7, P > χ2 = 0.0000, Log likelihood = − 113.6

AIC = 243.2

  1. * P-value < 0.05