Table 2 Association of clinico-pathologic parameters of micropapillary breast cancer subtype with ductal carcinoma, NOS
| Â | n (%) | P-value | ||
|---|---|---|---|---|
Micropapillary | Ductal, NOS | Total | ||
Age (years)ab | 48.20 ± 14.02 | 50.54 ± 12.48 | – | 0.47 |
Age group (n = 1710) | ||||
 ≤ 30 | 2 (13.3) | 89 (5.3) | 91 (5.3) | 0.323 |
 31–50 | 7 (46.7) | 822 (48.5) | 829 (48.5) | |
 51–70 | 5 (33.3) | 692 (40.8) | 697 (40.8) | |
 > 70 | 1 (6.7) | 92 (5.4) | 93 (5.4) | |
Tumor grade (n = 1710) | ||||
 Grade 1 | 0 (0) | 160 (9.4) | 160 (9.4) | 0.386 |
 Grade 2 | 11 (73.3) | 945 (55.8) | 956 (55.9) | |
 Grade 3 | 4 (26.7) | 590 (34.8) | 594 (34.7) | |
Ki67 valueab | 35.80 ± 22.94 | 35.92 ± 23.33 | – | 0.984 |
Ki67 index category (n = 1710) | ||||
 < 15 | 2 (13.3) | 373 (22) | 375 (21.9) | 0.582 |
 15–24 | 4 (26.7) | 311 (18.3) | 315 (18.4) | |
 25–44 | 5 (33.3) | 406 (24) | 411 (24) | |
 > 44 | 4 (26.7) | 605 (35.7) | 609 (35.6) | |
Size of tumorab | 33.11 ± 14.77 | 36.11 ± 14.84 | – | 0.547 |
Tumor stage (n = 643) | ||||
 T1 | 1 (11.1) | 83 (13.1) | 84 (13.1) | 1.000 |
 T2 | 7 (77.8) | 454 (71.6) | 461 (71.7) | |
 T3 | 1 (11.1) | 97 (15.3) | 98 (15.2) | |
Nodal status (n = 643) | ||||
 Positive | 6 (66.7) | 318 (50.2) | 324 (50.4) | 0.505 |
 Negative | 3 (33.3) | 316 (49.8) | 319 (49.6) | |
N stage (n = 643) | ||||
 N0 | 4 (44.4) | 320 (50.5) | 324 (50.4) | 0.417 |
 N1 | 2 (22.2) | 130 (20.5) | 132 (20.5) | |
 N2 | 0 (0) | 85 (13.4) | 85 (13.2) | |
 N3 | 3 (33.3) | 99 (15.6) | 102 (15.9) | |
Laterality (n = 1710) | ||||
 Left | 9 (60) | 865 (51) | 874 (51.1) | 0.489 |
 Right | 6 (40) | 830 (49) | 836 (48.9) | |
ER (n = 1710) | ||||
 Positive | 13 (86.7) | 1019 (60.1) | 1032 (60.4) | ≤ 0.05 |
 Negative | 2 (13.3) | 676 (39.9) | 678 (39.6) | |
PR (n = 1710) | ||||
 Positive | 11 (73.3) | 779 (46) | 790 (46.2) | ≤ 0.05 |
 Negative | 4 (26.7) | 916 (54) | 920 (53.8) | |
Her2neu (n = 1710) | ||||
 Positive | 9 (60) | 742 (43.8) | 751 (43.9) | 0.207 |
 Negative | 6 (40) | 953 (56.2) | 959 (56.1) | |
Lymphocytic infiltration (n = 643) | ||||
 Absent | 3 (33.3) | 364 (57.4) | 367 (57.1) | 0.241 |
 Moderate | 5 (55.6) | 210 (33.1) | 215 (33.4) | |
 Severe | 1 (9.5) | 60 (9.5) | 61 (9.5) | |
Insitu component (n = 642) | ||||
 Present | 2 (22.2) | 432 (68.2) | 434 (67.6) | ≤ 0.05 |
 Absent | 7 (77.8) | 201 (31.8) | 208 (32.4) | |
Lymphovascular invasion (n = 643) | ||||
 Present | 7 (77.8) | 157 (24.8) | 164 (25.5) | ≤ 0.05 |
 Absent | 2 (22.2) | 477 (75.2) | 479 (74.5) | |
Dermal lymphatic invasion (n = 643) | ||||
 Present | 2 (2.5) | 78 (12.3) | 80 (12.4) | 0.311 |
 Absent | 7 (77.8) | 556 (87.7) | 563 (87.6) | |
Pagetoid spread (n = 643) | ||||
 Present | 0 (0) | 14 (2.2) | 14 (2.2) | 1.000 |
 Absent | 9 (100) | 620 (97.8) | 629 (97.8) | |
Molecular subtypes (n = 1710) | ||||
 Triple negative | 1 (6.7) | 298 (17.6) | 299 (17.5) | ≤ 0.05 |
 HER 2 | 1 (6.7) | 363 (21.4) | 364 (21.3) | |
 Luminal A | 0 (0) | 287 (16.9) | 287 (16.8)) | |
 Luminal B | 13 (86.7) | 747 (44.1) | 760 (44.4) | |