Table 2 Effect of Duloxetine treatment on concentration of NO, nitrite, arginase and SOD activity from Ehrlich tumor-bearing mice
From: Tumor growth activity of duloxetine in Ehrlich carcinoma in mice
D5 | D30 | C | p | |
|---|---|---|---|---|
Spleen NO (mM) | 3.5 (2.5–4.5) | 6.4 (3.1–10.0) | 1.6 (0.8–4.0) | 0.080 |
Ascites NO (mM) | 13.9 (11.4–16.7) | 12.7 (7.0–19.6) | 12.6 (11.2–18.3) | 0.801 |
Ascites nitrite (mM) | 5.1 (4.9–7.1) | 5.0 (4.6–5.6) | 5.4 (4.9–5.6) | 0.499 |
Ascites arginase (unit/L) | 48.6 (45.8–51.4) | 52.9 (45.5–56.7) | 48.1 (36.7–67.7) | 0.690 |
Ascites SOD (% activity) | 92.5 (88.9–96.9)* | 91.6 (87.7–94.2)* | 87.6 (86.5–88.4) | 0.050 |