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Table 2 Drug related problems and causes in type 2 diabetes patients with hypertension

From: Determinants of drug-related problems among ambulatory type 2 diabetes patients with hypertension comorbidity in Southwest Ethiopia: a prospective cross sectional study

Variable category

Frequency (%)

Number of DRPs

 One

64 (21.3)

 Two

121 (40.3)

 Three

55 (18.3)

 Four

6 (2.0)

Category of DRP and its causes

 Need for additional drug therapy

145 (29.4)

  Medical condition requires the initiation of drug therapy

4 (2.8)

  Preventive drug therapy required to reduce the risk of developing a new condition

124 (85.5)

  Medical condition requires additional pharmacotherapy to attain synergistic or additive effects

12 (8.3)

  Required preventive drug therapy to reduce the risk of developing a new condition & a medical condition requires additional pharmacotherapy to attain synergistic or additive effects

5 (3.4)

 Ineffective drug

138 (27.9)

  The drug not the most effective for the medical problem

114 (82.6)

  The drug product is not effective for the indication being treated

24 (17.4)

  Dosage too low

78 (15.8)

  The dose is too low to produce the desired response

76 (97.4)

Drug interaction reduces the amount of active drug available

2 (2.6)

 Noncompliance

60 (12.2)

  The patient prefers not to take the medication

6 (10.0)

  The patient forgets to take the medication

27 (45.0)

  The drug product too expensive for the patient

3 (5.0)

  The patient prefers not to take the medication & the patient forgets to take the medication

17 (28.3)

  The patient forgets to take the medication & the drug product too expensive for the patient

5 (8.3)

  The patient prefers not to take the medication, the drug product too expensive for the patient & the patient forgets to take the medication

2 (3.3)

 Unnecessary drug therapy

51 (10.3)

  No valid medical indication for the drug

45 (88.2)

  Multiple drug products are being used for a condition that requires single drug therapy

4 (7.8)

  No valid medical indication for the drug & multiple drug products are being used for a condition that requires single drug therapy

2 (3.9)

 Adverse drug reaction

13 (2.6)

  The drug product causes an undesirable reaction that is not dose-related

7 (53.9)

  The drug product contraindicated due to risk factors

6 (46.2)

 Dosage too high

9 (1.8)

  Dose too high

7 (77.8)

  A drug interaction occurs resulting in a toxic reaction to the drug product

2 (22.2)