Table 2 Univariate and multivariate analysis for non-adherence to anti-TB therapy among TB patients attending TB clinic in health centers at Gondar town, Northwest Ethiopia, 2017 (n = 306)

Sex

 Male

0.84 (0.48, 1.45)

 Female

1

Age

 18–28

1

1

 29–38

1.29 (0.55, 3.04)

3.22 (0.68, 15.17)

 39–48

0.89 (0.38, 2.05)

0.83 (0.18, 3.88)

  ≥ 49

2.03 (0.96, 4.32)

2.44 (0.53, 9.41)

Marital status

 Single

0.24 (0.09, 0.69)*

0.11 (0.01, 1.60)

 Married

0.36 (013, 0.99)*

0.09 (0.01, 1.30)

 Divorced

0.42 (0.13, 1.38)

0.15 (0.01, 3.22)

 Widowed

1

1

Residence

 Urban

0.73 (0.36,1.46)

 Rural

1

Educational status

 Unable to read and write

0.59 (0.16, 2.12)

1.28 (0.21, 7.62)

 Able to read and write

2.62 (0.96, 7.12)

1.12 (0.20, 6.37)

 Grade 1–8

1.24 (0.40, 3.80)

0.41 (0.06, 3.01)

 Grade 9–12

1.01 (0.35, 2.93)

2.12 (0.34, 13.11)

 Diploma

1.10 (0.30, 4.07)

1.48 (0.19, 11.66)

 Degree and above

1

1

Income (Ethiopian Birr)

 ≤ 1000

1

1

 1001–2000

1.12 (0.59, 2.12)

1.65 (0.50, 5.51)

 2001–3000

0.52 (0.21, 1.27)

0.47 (0.09, 2.38)

 > 3000

0.44 (0.16, 1.22)

0.12 (0.01, 1.30)

Distance from TB clinic (single trip) (km)

 < 3

1

1

 3–5

2.58 (0.94, 7.08)

1.83 (0.38, 8.78)

 > 5

8.51 (3.12, 23.18*

4.30 (0.80, 23.16)

Type of transportation to the TB clinic

 Walking/foot

1

1

 Public transport

1.88 (0.95, 3.73)

1.80 (0.54, 6.01)

Traveling time (single trip) (min)

 ≤ 30

0.30 (0.16, 0.55)*

0.48 (0.11, 2.11)

 > 30

1

1

Cost of traveling (single trip) (n = 222) (Ethiopian Birr)

 ≤ 10 Birr

0.40 (0.21, 0.77)*

1.14 (0.25, 5.24)

 > 10 Birr

1

1

Patients category

 New

1

1

 Treatment failure

1.64 (0.63, 4.17)

0.52 (0.05, 5.12)

 Relapse

0.88 (0.32, 2.43)

0.94 (0.19, 4.75)

 Return after default

3.75 (1.37, 10.27)*

0.88 (0.05, 14.39)

Treatment phase

 Intensive phase

1

1

 Continuation phase

2.70 (1.53, 4.78)*

2.27 (1.5, 5.94)

HIV status

 Seronegative

2.30 (1.19, 4.46)*

1.97 (0.41, 9.39)

 Seropositive

1

1

TB status disclosure to the family

 Yes

1

1

 No

1.74 (0.94, 3.22)

1.47 (0.31, 6.90)

Number of comorbidity?

 > 1

5.23 (2.81, 9.74)

6.22 (2.21, 17.48)**

 No or 1

1

1

Knowledge

 Good knowledge

1

1

 Poor knowledge

4.13 (2.29, 7.44)*

4.11 (1.57, 10.75)**

Patient-provider relationship

 Good patient-provider relationship

1

1

 Poor patient-provider relationship

3.25 (1.84, 5.75)*

4.60 (1.63, 12.97)**

Alcohol intake

 Yes

3.22 (1.73, 6.00)*

5.03 (1.54, 16.40)**

 No

1

1