Skip to main content

Table 2 Genotype effect on demographic and clinical characteristics within PAOG group

From: Plexin domain containing 2 (PLXDC2) gene polymorphism rs7081455 may not influence POAG risk in a Saudi cohort

Characteristics

Genotypes

p valuea

T/T (n = 47)

No. (%)

T/G (n = 88)

No. (%)

G/G (n = 53)

No. (%)

Demographic

 Age in years, mean (SD)

59.0 (11.3)

61.2 (11.0)

62.2 (9.4)

0.305*

 Male

27 (57.4)

49 (55.6)

28 (52.8)

0.894

 Female

20 (42.5)

39 (44.3)

25 (47.1)

Medical history

 Family history of glaucoma

5 (10.6)

7 (7.9)

6 (11.3)

0.773

 Smoking

8 (17.0)

7 (7.9)

5 (9.4)

0.251

 Diabetes mellitus

18 (38.3)

37 (42.0)

20 (37.7)

0.851

 Hypertension

15 (31.9)

34 (38.6)

22 (41.5)

0.598

 Coronary artery disease

1 (2.1)

3 (3.4)

2 (3.7)

0.885

 Hypercholesterolemia

1 (2.1)

7 (7.9)

5 (9.4)

0.310

Glaucoma indices

 Intraocular pressure, mmHg, mean (SD)

22.3 (8.1)

23.7 (8.8)

23.2 (10.3)

0.536**

 Cup/disc ratio

0.77 (0.2)

0.81 (0.6)

0.75 (0.2)

0.736**

 Number of anti-glaucoma medications

1.6 (0.9)

1.9 (1.1)

1.8 (1.2)

0.214**

  1. aPearson Chi2 test
  2. * One-way ANOVA
  3. ** Kruskal–Wallis test