Table 1 Baseline characteristics of surgical patients with sepsis
Parameter | All surgical patients (n = 435) | Patients who received an RBC transfusion (n = 302) | Patients without an RBC transfusion (n = 133) | P value |
|---|---|---|---|---|
Age (years) | 62 ± 15 | 63 ± 15 | 61 ± 15 | 0.25 |
Gender (male %) | 64 | 63 | 65 | 0.66 |
BMI (kg/m2) | 27 ± 6 | 27 ± 5 | 28 ± 7 | 0.93 |
Septic shock (day 1) [%] | 63 | 69 | 51 | 0.0004 |
SOFA score (day 1) | 8.9 ± 3.7 | 9.5 ± 3.8 | 7.5 ± 3.0 | < 0.001 |
APACHE II score (day 1) | 20.8 ± 6.5 (n = 430) | 21.6 ± 6.6 (n = 300) | 19.0 ± 6.1 (n = 130) | 0.0002 |
Comorbidities (%) | ||||
Arterial hypertension | 52 | 50 | 56 | 0.22 |
Previous myocardial infarction | 5 | 6 | 2 | 0.12 |
COPD | 12 | 14 | 8 | 0.12 |
Kidney disease | 9 | 10 | 6 | 0.22 |
Diabetes mellitus (insulin-dependent) | 9 | 10 | 9 | 0.85 |
Diabetes mellitus (not insulin-dependent) | 8 | 7 | 10 | 0.31 |
Chronic liver disease | 6 | 7 | 4 | 0.24 |
Malignant tumour | 20 | 23 | 12 | 0.0072 |
Stroke | 6 | 4 | 10 | 0.0266 |
Site of infection (%) | ||||
Pulmonary | 56 | 52 | 66 | 0.14 |
Abdominal | 28 | 32 | 16 | 0.0457 |
Bones or soft tissues | 4 | 5 | 2 | 0.45 |
Surgical wounds | 2 | 2 | 2 | 0.54 |
Urogenital | 2 | 2 | 3 | 0.73 |
Primary bacteraemia | 4 | 5 | 2 | 0.58 |
Other | 4 | 2 | 7 | 0.0130 |
Organ support (day 1) [%] | ||||
Mechanical ventilation | 85 | 86 | 83 | 0.53 |
Vasopressors | 63 | 69 | 51 | 0.0004 |
Renal replacement therapy | 7 | 9 | 2 | 0.0042 |
Medication with statins [%] | 20 | 22 | 16 | 0.13 |