Table 1 Characteristics of included studies
Study | Country | Study period | No. of participants (in final analysis) | Gestational age (weeks) | Birth weight (g) | Age at screening (days) |
|---|---|---|---|---|---|---|
Hill et al. 1974 (I) [8] | USA | 1972 | 31 | 28–38 | 1100–3380 | 3–90 |
Hill et al. 1974 (II) [8] | USA | 1972 | 23 | 28–38 | 1100–3380 | 3–90 |
Parry et al. 1980 [9] | USA | 1978 | 128 | NR | NR | NR |
Samuelsson et al. 2014 [1] | Sweden | 2006–2011 (recurrent outbreaks) | 38 | 25 (36 for controls) | 725 (2570 for controls) | NR |
Tsiatsiou et al. 2015 [10] | Greece | 2011 | 96 | 26–40 | 800–4300 | 10–80 |
Study | Screening interval (s) | Screening location | Outbreak bacteria species/strain | Definition of sepsis | Control measures | Risk of bias |
|---|---|---|---|---|---|---|
Hill et al. 1974 (I) [8] | Weekly | Rectal/respiratory | Klebsiella pneumoniae type 26 | NR | Enhanced handwashing; use of long-sleeved gowns; isolation | High |
Hill et al. 1974 (II) [8] | Weekly | Rectal/respiratory | Klebsiella pneumoniae type 26 | NR | Enhanced handwashing; use of long-sleeved gowns; isolation | High |
Parry et al. 1980 [9] | Daily | Nose/throat/umbilicus/rectum | Citrobacter diversus | NR | Closure of nursery; sterile cleaning; cohorting | High |
Samuelsson et al. 2014 [1] | Weekly | Nose/throat/perineum/rectum | Serratia marcescens | Positive blood culture plus ≥ 2 additional criteria; or: negative blood culture plus ≥ 3 additional criteriaa | Hand hygiene; cleaning; handling of venous catheters; distribution of patients in room; antibiotics | High |
Tsiatsiou et al. 2015 [10] | Weekly | Perianal/stool | Carbapenem-resistant Acinetobacter baumannii | NR | Antimicrobial therapy; closure of department to new admissions | High |