Fig. 1
From: Improving selectivity of DNA–RNA binding zinc finger using directed evolution
Schematic illustration of interaction between ZfQQR and the recognition sequence in DNA–RNA hybrid substrate. a Three zinc finger modules. b Zfm2 module and Zfm2 library design. The amino acid residues directly contacting bases of the substrate are labelled in blue. c Three zinc finger modules and the L5 and L6 libraries design. The sequence of the amino acid residues of the Zfm2–Zfm3 linker is shown in red