Fig. 1
From: PAD-Beads enrichment enhances detection of PrPSc using real-time quaking-induced conversion
Comparison of RT-QuIC reactions between scrapie infected sheep brain homogenate (a, c) and PAD-Beads treated scrapie infected sheep brain homogenate (b, d). Comparison of rate constant obtained RT-QuIC reactions between scrapie infected sheep brain homogenate (e) and PAD-Beads treated scrapie infected sheep brain homogenate (f). RT-QuIC reactions were run using full-length (23–231) bank vole prion protein as the substrate with the addition of 0.001% SDS in the presence of 300 mM NaCl. Data are presented as mean ThT fluorescence of 4 technical replicates