Fig. 1
From: covRNA: discovering covariate associations in large-scale gene expression data
covRNA’s statistical test is shown to control the type I error rate correctly. A p-value distribution under the null hypothesis of covRNA’s statistical test between sample and gene annotations for n = 1000 permutations is generated. The results of the permutation of one random sample annotation-gene annotation association are shown here. a Histogram of the resulting p-values. b Q–Q plot of the p-values