Fig. 1

Dissolution profiles of a reference and seven generic enteric-coated 50 mg diclofenac sodium tablet formulations available on the Saudi market. R, reference, G1 to G7, generic formulations. Eight units of each formulation were studied. Mean (SD) amount of drug released at the specified times are shown on the left axis (continuous line) and percent of label amount released on the right axis (interrupted line). Time 0 min indicates amount released after 120 min in 0.1 N HCl. Other times indicate amount released in phosphate buffer (pH 6.8). Time 105 min indicates amount released with a stirring rate of 250 rpm for 15 min (infinity), otherwise, stirring rate was 50 ± 1 rpm, using USP dissolution apparatus type II (paddle apparatus) and a temperature of 37 ± 0.5 °C. Formulations’ label details are available in Additional file 1, Label information