Fig. 2From: R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeabilityRSPO2 deficiency promotes neutrophil accumulation. a, b Quantification of ICC of MPO + cells in the BALF of RSPO2+/+ mice and RSPO2−/− mice 48 h after TM administration. An arrow indicates examples of DAPI/MPO-double stained cells. c qPCR analysis demonstrating a similar increase in MPO transcript in cells present in BALF of RSPO2−/− mice. Representative images are shown from RSPO2+/+ mice (n = 3) and RSPO2−/− mice (n = 3) samples. * = A P value of less than 0.05 was considered significantBack to article page