Fig. 1
From: Quality assessment of nine paracetamol 500 mg tablet brands marketed in Saudi Arabia
Dissolution profiles of two references and seven generic paracetamol 500 mg tablet brands available on the Saudi market. Mean (SD) amount of drug released at the specified times are shown on the left axis (continuous line) and percent of label amount released on the right axis (interrupted line). United States Pharmacopoeia (USP) dissolution apparatus type II (paddle apparatus) was used with a stirring rate of 50 ± 1 rpm (except for “infinity” time) and a temperature of 37 ± 0.5 ºC. Brands’ label details are available in Additional file 1: Table S1. Label information. R1 and R2, reference brands; G1 to G7, generic brands. Dissolution medium was phosphate buffer (pH 5.8). Time 75 min indicates amount released with a stirring rate of 150 rpm for 15 min (“infinity”)