Fig. 2
Canonical pathways identified with Ingenuity pathway analysis using the list of 567 differentially expressed genes (Padjusted < 0.05). A illustrates the percentage of genes that were up- or down-regulated in each canonical pathway. B specifically illustrates the dTMP de novo biosynthesis, folate polyglutamation and folate transformations I pathways and the involvement of differentially expressed genes SHMT1 and SHMT2