Fig. 2

Evaluation of CUT&RUN peaks for transcription factors and histone modifications with replicates using the ssvQC package. The ssvQC output plots for H3K4me3 and Ikaros CUT&RUN replicates from frozen B cells, showing A total mapped reads, B total number of called peaks, C fraction of reads in peaks (FRiP) scores D Genome-wide correlations of reads in 10 kb bins. The overlaps of peak regions for E H3K4me3 and F Ikaros were compared via binary heatmap, upset, and venn diagrams