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  1. Major Histocompatibility Complex (MHC) has drawn the attention of evolutionary biologists due to its importance in crucial biological processes, such as sexual selection and immune response in jawed vertebrate...

    Authors: David Canal, Miguel Alcaide, Jarl A Anmarkrud and Jaime Potti
    Citation: BMC Research Notes 2010 3:236
  2. Chronic complications of diabetes can be reduced through optimal glycemic and lipid control as evaluated through measurement of glycosylated hemoglobin (A1C) and low-density lipoprotein cholesterol (LDL-C). We...

    Authors: Helena Klomp, Roland F Dyck, Nirmal Sidhu, Paul J Cascagnette and Gary F Teare
    Citation: BMC Research Notes 2010 3:233
  3. The longitudinal epidemiology of major depressive episodes (MDE) is poorly characterized in most countries. Some potentially relevant data sources may be underutilized because they are not conducive to estimat...

    Authors: Scott B Patten
    Citation: BMC Research Notes 2010 3:231
  4. Hematologic manifestations of the human immunodeficiency virus (HIV) infection are a well-recognized complication of the disease and may be clinically important. Our objective was to determine the risk factors...

    Authors: José A Mata-Marín, Jesús E Gaytán-Martínez, Rosa E Martínez-Martínez, Carla I Arroyo-Anduiza, José L Fuentes-Allen and Moisés Casarrubias-Ramirez
    Citation: BMC Research Notes 2010 3:230
  5. Self-conscious emotions (shame, guilt and embarrassment) are part of many individuals' experiences of seeking STI testing. These emotions can have negative impacts on individuals' interpretations of the STI te...

    Authors: Myles Balfe, Ruairi Brugha, Diarmuid O' Donovan, Emer O' Connell and Deirdre Vaughan
    Citation: BMC Research Notes 2010 3:229
  6. Studies from iodine-sufficient areas have shown that a high proportion of patients taking medication for thyroid diseases have thyroid stimulating hormone (TSH) levels outside the reference range. Next to pati...

    Authors: Anke Hannemann, Nele Friedrich, Robin Haring, Alexander Krebs, Henry Völzke, Dietrich Alte, Matthias Nauck, Thomas Kohlmann, Hans-Christof Schober, Wolfgang Hoffmann and Henri Wallaschofski
    Citation: BMC Research Notes 2010 3:227
  7. MODELLER is a program for automated protein Homology Modeling. It is one of the most widely used tool for homology or comparative modeling of protein three-dimensional structures, but most users find it a bit ...

    Authors: Bhusan K Kuntal, Polamarasetty Aparoy and Pallu Reddanna
    Citation: BMC Research Notes 2010 3:226
  8. The Asteraceae represents an important plant family with respect to the numbers of species present in the wild and used by man. Nonetheless, genomic resources for Asteraceae species are relatively underdevelop...

    Authors: Lucy Gonthier, Arnaud Bellec, Christelle Blassiau, Elisa Prat, Nicolas Helmstetter, Caroline Rambaud, Brigitte Huss, Theo Hendriks, Hélène Bergès and Marie-Christine Quillet
    Citation: BMC Research Notes 2010 3:225
  9. The innate immune system employs several receptor families that form the basis of sensing pathogen-associated molecular patterns. NOD (nucleotide-binding and oligomerization domain) like receptors (NLRs) compr...

    Authors: Marcel Kramer, Janne Boeck, Daniela Reichenbach, Christoph Kaether, Stefan Schreiber, Matthias Platzer, Philip Rosenstiel and Klaus Huse
    Citation: BMC Research Notes 2010 3:224
  10. Several high-density oligonucleotide microarray platforms are available for genome-wide single nucleotide polymorphism (SNP) detection and microarray-based comparative genomic hybridisation (array CGH), which ...

    Authors: Stine H Kresse, Karoly Szuhai, Ana H Barragan-Polania, Halfdan Rydbeck, Anne-Marie Cleton-Jansen, Ola Myklebost and Leonardo A Meza-Zepeda
    Citation: BMC Research Notes 2010 3:223
  11. In animals mtDNA inheritance is maternal except in certain molluscan bivalve species which have a paternally inherited mitochondrial genome (genome M) along with the standard maternal one (genome F). Normally,...

    Authors: Eleni Kyriakou, Eleftherios Zouros and George C Rodakis
    Citation: BMC Research Notes 2010 3:222
  12. The first objective of a DNA microarray experiment is typically to generate a list of genes or probes that are found to be differentially expressed or represented (in the case of comparative genomic hybridizat...

    Authors: Emma Laing and Colin P Smith
    Citation: BMC Research Notes 2010 3:221
  13. α-Santalol, an active component of sandalwood oil, has shown chemopreventive effects on skin cancer in different murine models. However, effects of α-santalol on cell cycle have not been studied. Thus, the obj...

    Authors: Xiaoying Zhang, Wei Chen, Ruth Guillermo, Gudiseva Chandrasekher, Radhey S Kaushik, Alan Young, Hesham Fahmy and Chandradhar Dwivedi
    Citation: BMC Research Notes 2010 3:220
  14. The miR-200c/141 cluster has recently been implicated in the epithelial to mesenchymal transition (EMT) process. The expression of these two miRNAs is inversely correlated with tumorigenicity and invasiveness ...

    Authors: Rui Neves, Christina Scheel, Sandra Weinhold, Ellen Honisch, Katharina M Iwaniuk, Hans-Ingo Trompeter, Dieter Niederacher, Peter Wernet, Simeon Santourlidis and Markus Uhrberg
    Citation: BMC Research Notes 2010 3:219
  15. Anthroposophic medicine is a physician-provided complementary therapy system involving counselling, artistic and physical therapies, and special medications. The purpose of this analysis was to identify predic...

    Authors: Harald J Hamre, Claudia M Witt, Gunver S Kienle, Anja Glockmann, Stefan N Willich and Helmut Kiene
    Citation: BMC Research Notes 2010 3:218
  16. Although altruism is a key principle in our current organ donation and transplantation system, the meanings and implications of the term have been widely debated. Recently, a new type of living organ donation-...

    Authors: Marie-Chantal Fortin, Marianne Dion-Labrie, Marie-Josée Hébert and Hubert Doucet
    Citation: BMC Research Notes 2010 3:216
  17. Clock family genes encode transcription factors that regulate clock-controlled genes and thus regulate many physiological mechanisms/processes in a circadian fashion. Clock1 duplicates and copies of Clock3 and...

    Authors: Marion I Paibomesai, Hooman K Moghadam, Moira M Ferguson and Roy G Danzmann
    Citation: BMC Research Notes 2010 3:215
  18. SNP (Single Nucleotide Polymorphism) discovery is now routinely performed using high-throughput sequencing of reduced representation libraries. Our objective was to adapt 454 GS FLX based sequencing methodolog...

    Authors: Sophie Leroux, Katia Feve, Florence Vignoles, Olivier Bouchez, Christophe Klopp, Céline Noirot, David Gourichon, Sabine Richard, Christine Leterrier, Catherine Beaumont, Francis Minvielle, Alain Vignal and Frédérique Pitel
    Citation: BMC Research Notes 2010 3:214
  19. The methylenetetrahydrofolate reductase (MTHFR) gene variant C677T has been implicated as a genetic risk factor in migraine susceptibility, particularly in Migraine with Aura. Migraine, with and without aura (...

    Authors: Annie Liu, Saraswathy Menon, Natalie J Colson, Sharon Quinlan, Hannah Cox, Madelyn Peterson, Thomas Tiang, Larisa M Haupt, Rod A Lea and Lyn R Griffiths
    Citation: BMC Research Notes 2010 3:213
  20. Southern China is a major area for endemic nasopharyngeal carcinoma (NPC). Genetic factors as well as environmental factors play a role in development of NPC. To investigate the roles of previously described c...

    Authors: Xiuchan Guo, Yi Zeng, Hong Deng, Jian Liao, Yuming Zheng, Ji Li, Bailey Kessing and Stephen J O'Brien
    Citation: BMC Research Notes 2010 3:212
  21. The isolation of DNA-free RNA is a crucial step in the reverse transcription PCR (RT-PCR). Every RNA extraction procedure results in RNA samples contaminated with genomic DNA, which can cause false-positive ou...

    Authors: Lydia V Rump, Benedicta Asamoah and Narjol Gonzalez-Escalona
    Citation: BMC Research Notes 2010 3:211
  22. Epithelial cells are exposed to a variety of mechanical stimuli. Epithelial Na+ channels (ENaC) mediate sodium transport across apical membranes of epithelial cells that line the distal nephron, airway and alveol...

    Authors: Alexey V Karpushev, Daria V Ilatovskaya and Alexander Staruschenko
    Citation: BMC Research Notes 2010 3:210
  23. Counselling on the danger signs of unpredictable obstetric complications and the appropriate management of such complications are crucial in reducing maternal mortality. The objectives of this study were to id...

    Authors: Malabika Sarker, Gerhard Schmid, Elin Larsson, Sylvia Kirenga, Manuela De Allegri, Florian Neuhann, Theodora Mbunda, Isaack Lekule and Olaf Müller
    Citation: BMC Research Notes 2010 3:209
  24. Many studies have been done to find out the molecular mechanism of systemic acquired resistance (SAR) in plants in the past several decades. Numbers of researches have been carried out in the model plants such...

    Authors: Jiyu Zhang, Xiaoli Du, Qingju Wang, Xiukong Chen, Dong Lv, Kuanyong Xu, Shenchun Qu and Zhen Zhang
    Citation: BMC Research Notes 2010 3:208
  25. The aim of this study was to evaluate the safety and efficacy of outpatient laparoscopic cholecystectomy (OLC) in a day surgery unit in a teaching hospital. OLC was offered to patients with symptomatic choleli...

    Authors: Athanasios Marinis, Emmanouil Stamatakis, Athanasia Tsaroucha, Nikolaos Dafnios, Georgios Anastasopoulos, Georgios Polymeneas and Theodosios Theodosopoulos
    Citation: BMC Research Notes 2010 3:207
  26. Long-term acute care hospitals (LTACs) provide specialized care for patients recovering from severe acute illness. In order to facilitate research into LTAC utilization and outcomes, we studied whether or not ...

    Authors: Jeremy M Kahn and Theodore J Iwashyna
    Citation: BMC Research Notes 2010 3:205
  27. The anabolic steroid, dehydroepiandosterone sulfate (DHEA-S), is secreted from the adrenal cortex. It plays a significant role in the body as a precursor to sex steroids as well as a lesser known role in the h...

    Authors: Courtney A Whetzel and Laura C Klein
    Citation: BMC Research Notes 2010 3:204
  28. General transcription factor (TFII-I) is a multi-functional transcription factor encoded by the Gtf2i gene, that has been demonstrated to regulate transcription of genes critical for development. Because of th...

    Authors: Iwona Fijalkowska, Deva Sharma, Carol J Bult and Sonye K Danoff
    Citation: BMC Research Notes 2010 3:203
  29. Propofol is a commonly used intravenous anesthetic agent, which produce rapid induction of and recovery from general anesthesia. Numerous clinical studies reported that propofol can potentially cause amnesia a...

    Authors: Srivatsan Kidambi, Joel Yarmush, Yevgeny Berdichevsky, Sangeetha Kamath, Wayne Fong and Joseph SchianodiCola
    Citation: BMC Research Notes 2010 3:201
  30. Accurate prognosis is vital to the initiation of advance care planning particularly in a vulnerable, at risk population such as care home residents. The aim of this paper is to report on the revision and simpl...

    Authors: Davina Porock, Debra Parker-Oliver, Gregory F Petroski and Marilyn Rantz
    Citation: BMC Research Notes 2010 3:200
  31. The advancements in DNA sequencing technologies have allowed researchers to progress from the analyses of a single organism towards the deep sequencing of a sample of organisms. With sufficient sequencing dept...

    Authors: Kelvin Li, Eli Venter, Shibu Yooseph, Timothy B Stockwell, Lance D Eckerle, Mark R Denison, David J Spiro and Barbara A Methé
    Citation: BMC Research Notes 2010 3:199
  32. Chronic obstructive pulmonary disease (COPD) and asthma are considered underdiagnosed and misdiagnosed chronic diseases. In The Netherlands, a COPD-asthma telemedicine service has been developed to increase GP...

    Authors: Ioanna G Tsiligianni, Thys van der Molen, Nikolaos E Tzanakis, Nikolaos M Siafakas, Ellen van Heijst and Christos Lionis
    Citation: BMC Research Notes 2010 3:198
  33. Apoptosis is a highly ordered and orchestrated multiphase process controlled by the numerous cellular and extra-cellular signals, which executes the programmed cell death via release of cytochrome c alterations i...

    Authors: Katarzyna Kokoszyńska, Leszek Rychlewski and Lucjan S Wyrwicz
    Citation: BMC Research Notes 2010 3:197
  34. About 130 million people are infected with the hepatitis C virus (HCV) worldwide, but effective treatment options are not yet available. One of the most promising targets for antiviral therapy is nonstructural...

    Authors: Paola JS Provazzi, Helen A Arcuri, Isabel Maria VG de Carvalho-Mello, João Renato R Pinho, Maurício L Nogueira, Mário S Palma and Paula Rahal
    Citation: BMC Research Notes 2010 3:196
  35. The variability of maternal serum biochemical markers for Down syndrome, free β-hCG and PAPP-A can have a different impact on false-positive rates between the 10+0 and 13+6 week of gestation. The study populat...

    Authors: Dubravka Tišlarić-Medenjak, Ivana Zec, Ana-Maria Šimundić, Senka Sabolović-Rudman, Milan Kos and Željka Bukovec Megla
    Citation: BMC Research Notes 2010 3:194
  36. Routine rapid testing for Bovine Spongiform Encephalopathy (BSE) has highlighted some problems with BSE rapid test performance, the most significant being the number of initially reactive samples and the false...

    Authors: Daniela Meloni, Katia Varello, Marzia Pezzolato, Elsa Manzardo, Maria C Cavarretta, Francesco Ingravalle, Maria Caramelli and Elena Bozzetta
    Citation: BMC Research Notes 2010 3:193
  37. A complete gene-expression microarray should preferably detect all genomic sequences that can be expressed as RNA in an organism, i.e. the transcriptome. However, our knowledge of a transcriptome of any organi...

    Authors: Han Rauwerda, Mark de Jong, Wim C de Leeuw, Herman P Spaink and Timo M Breit
    Citation: BMC Research Notes 2010 3:192
  38. Numerous models, of variable quality, exist to impart the complex skills required to perform vascular anastomosis. These models differ with regard to the kinds of materials used, as well as their sizes, the ti...

    Authors: Philipe N Khalil, Axel Kleespies, Markus Rentsch, Wolfgang E Thasler, Karl-Walter Jauch and Christiane J Bruns
    Citation: BMC Research Notes 2010 3:189
  39. Trauma is a major health problem in the United Arab Emirates (UAE) as well as worldwide. Trauma registries provide large longitudinal databases for analysis and policy improvement. We aim in this paper to repo...

    Authors: Sami Shaban, Hani O Eid, Ezedin Barka and Fikri M Abu-Zidan
    Citation: BMC Research Notes 2010 3:187

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