SNP | Controls | CD | UC | CD+UC | |||
---|---|---|---|---|---|---|---|
n (%) | n (%) | OR (95% CI) | n (%) | OR (95% CI) | n (%) | OR (95% CI) | |
NOD1 rs2075818 | |||||||
CC | 105 (52.2) | 255 (66.7) | 1.29 (0.56–2.98) | 226 (56.5) | 0.61 (0.28–1.31) | 481 (61.4) | 0.84 (0.40–1.77) |
CG | 87 (43.3) | 111 (29.0) | 0.68 (0.29–1.59) | 142 (35.5) | 0.46 (0.21–1.01) | 253 (32.3) | 0.53 (0.25–1.13) |
GG | 9 (4.5) | 17 (4.4) | 1.00 | 32 (8.0) | 1.00 | 49 (6.3) | 1.00 |
Genotype p-value | 0.002 | 0.08 | 0.01 | ||||
HWE p-value | 0.10 | 0.28 | 0.15 | 0.05 | |||
G | 105 (26.1) | 145 (18.9) | 206 (25.8) | 351 (22.4) | |||
C | 297 (73.9) | 621 (81.1) | 594 (74.3) | 1215 (77.6) | |||
OR (95% CI) | 0.66 (0.49–0.89) | 0.98 (0.74–1.30) | 0.82 (0.63–1.06) | ||||
Allelic p-value | 0.004 | 0.89 | 0.12 | ||||
NOD1 rs2075822 | |||||||
CC | 20 (10.0) | 28 (7.3) | 1.00 | 17 (4.2) | 1.00 | 45 (5.7) | 1.00 |
CT | 60 (30.0) | 122 (31.9) | 1.45 (0.76–2.79) | 135 (33.6) | 2.65 (1.29–5.41) | 257 (32.8) | 1.90 (1.05–3.46) |
TT | 120 (60.0) | 232 (60.7) | 1.38 (0.75–2.55) | 250 (62.2) | 2.45 (1.23–4.85) | 482 (61.5) | 1.79 (1.02–3.14) |
Genotype p-value | 0.52 | 0.02 | 0.09 | ||||
HWE p-value | 0.007 | 0.04 | 0.82 | 0.17 | |||
C | 100 (25.0) | 178 (23.3) | 169 (21.0) | 347 (22.1) | |||
T | 300 (75.0) | 586 (76.7) | 635 (79.0) | 1221 (77.9) | |||
OR (95% CI) | 0.91 (0.69–1.21) | 0.80 (0.60–1.06) | 0.85 (0.66–1.10) | ||||
Allelic p-value | 0.52 | 0.12 | 0.22 | ||||
NOD1 rs2907748 | |||||||
AA | 21 (10.3) | 31 (8.2) | 1.00 | 20 (5.0) | 1.00 | 51 (6.6) | 1.00 |
AG | 73 (36.7) | 129 (34.3) | 1.20 (0.64–2.23) | 161 (40.3) | 2.32 (1.18–4.53) | 290 (37.4) | 1.64 (0.93–2.89) |
GG | 105 (52.8) | 216 (57.4) | 1.39 (0.76–2.54) | 219 (54.7) | 2.19 (1.14–4.22) | 435 (56.1) | 1.71 (0.98–2.96) |
Genotype p-value | 0.48 | 0.04 | 0.16 | ||||
HWE p-value | 0.12 | 0.07 | 0.16 | 0.78 | |||
A | 115 (28.9) | 191 (25.4) | 201 (25.1) | 392 (25.3) | |||
G | 283 (71.1) | 561 (74.6) | 599 (74.9) | 1160 (74.7) | |||
OR (95% CI) | 0.84 (0.64–1.10) | 0.83 (0.63–1.08) | 0.83 (0.65–1.06) | ||||
Allelic p-value | 0.20 | 0.16 | 0.14 |