Skip to main content

Table 2 Specific Analogous Factors of Invasive Behavior

From: A systems biology approach to invasive behavior: comparing cancer metastasis and suburban sprawl development

Cancer

Sprawl

Fractal growth pattern limited by

natural barriers.

Fractal growth pattern limited by natural

and man-made barriers

Initiation by growth factors and

altered cell signaling

Initiated by profit-based speculative development

Loss of p53 function

Low cost gasoline

Loss of cellular differentiation,

expansion of clonal populations

Segregated land use and

loss of differentiated architecture

Critical need for angiogenesis,

often conducted poorly by tumors

Powerful effects of road development,

often constructed in an inefficient manner

Cachexia and Infection

Urban blight