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Table 1 Association (odds ratio, OR, with 95% confidence interval, CI) of low avidity HPV16 antibodies (ab) with increased risk of being seropositive for other HPV types among Finnish and Ugandan women.

From: Low avidity of human papillomavirus (HPV) type 16 antibodies is associated with increased risk of low-risk but not high-risk HPV type prevalence

Population

Seropositivity

Total

Prevalence of low ab-avidity (%)

Crude OR (95% CI)

Finland (n = 248)

HPV16 only

113

19 (7.7%)

1

 

HPV16 + 6 or 11

36

8 (6.3%)

1.4 (0.6-3.6)

 

HPV16 + 31 or 33

59

5 (2.5%)

0.5 (0.2-1.3)

 

HPV16 + 18 or 45

40

6 (2.2%)

0.9 (0.3-2.4)

Uganda (n = 117)

HPV16 only

45

9 (7.7%)

1

 

HPV16 + 6 or 11

32

15 (12.8%)

3.5 (1.3-9.7)

 

HPV16 + 31 or 33

24

4 (3.4%)

0.8 (0.2-2.9)

 

HPV16 + 18 or 45

16

2 (1.7%)

0.6 (0.1-4.0)

All (n = 365)

HPV16 only

158

28 (7.7%)

1

 

HPV16 + 6 or 11

68

23 (6.3%)

2.4 (1.3-4.6)

 

HPV16 + 31 or 33

83

9 (2.5%)

0.6 (0.3-1.3)

 

HPV16 + 18 or 45

56

8 (2.2%)

0.8 (0.3-1.8)

  1. All = combined data of Finnish and Ugandan women
  2. Cutoff_30% = using low avidity controls mean plus 3 standard deviations