| Concentration | Viability (%) |
---|
Freshly isolated LC | - | 94.4 ± 2.1 |
36 h cultured LC | - | 73.3 ± 2.8 |
Prednisone | 10-6 M | 69.9 ± 3.7 |
| 10-8 M | 66.7 ± 5.5 |
Thalidomide | 10-6 M | 63.5 ± 3.2 |
| 10-8 M | 61.4 ± 2.1 |
Cyclosporine A | 10-6 M | 62.2 ± 6.4 |
| 10-8 M | 61.2 ± 10.7 |
Amitriptyline | 10-6 M | 66.2 ± 2.2 |
| 10-8 M | 64.6 ± 1.7 |
- aPurified LC were cultured for 36 h in the presence or absence of 10-6 M or 10-8 M prednisone, thalidomide, cyclosporine A, or amitriptyline. Cell viability was then assessed using propidium iodide. All results are shown as mean ± SD for three independent experiments, which did not vary significantly from the control.