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Table 1 List of genes down regulated upon Cyclin T2 and Cyclin T1 depletion

From: Limited redundancy in genes regulated by Cyclin T2 and Cyclin T1

Gene name

Gene ID

Gene identifier

Probe ID

Chromosome

Fold-change

p-value

Top 10 genes down-regulated by Cyclin T2 depletion

Heat shock 27 kDa protein 3

HSPB3

NM_006308

206375_s_at

5

-3.12

0.0368

G protein-coupled receptor 137B

GPR137B

NM_003272

204137_at

1

-2.3

0.0251

ATP-binding cassette, sub-family A (ABC1), member 1

ABCA1

NM_005502

203504_s_at

9

-2.1

0.0336

Ankyrin repeat domain 12

ANKRD12

X80821

216563_at

18

-2.06

0.0166

Ataxin 1

ATXN1

AW235612

203231_s_at

6

-2.04

0.0111

Coronin 6

CORO6

NM_032854

1552301_a_at

17

-2.04

0.0330

Growth arrest-specific 1

GAS1

NM_002048

204457_s_at

9

-2.02

0.0303

ATG16 autophagy related 16-like 1(S. cerevisiae)

ATG16L1

NM_017974

220521_s_at

2

-1.95

0.0375

Hexamethylene bis-acetamide inducible 1

HEXIM1

NM_006460

202815_s_at

17

-1.94

0.0482

Calcium channel, voltage-dependent, beta 2 subunit

CACNB2

NM_000724

207776_s_at

10

-1.85

0.0178

Top 10 genes down-regulated by Cyclin T1 depletion

Chemokine (C-X-C motif) ligand 14

CXCL14

NM_004887

218002_s_at

5

-3.55

0.0403

Transmembrane protease, serine 3

TMPRSS3

AB038160

223949_at

21

-2.59

0.0361

Ankyrin repeat domain 29

ANKRD29

AI307802

238332_at

18

-2.36

0.0433

FK506 binding protein 1B, 12.6kDa

FKBP1B

NM_004116

206857_s_at

2

-2.16

0.0108

Syndecan binding protein (syntenin)

SDCBP

NM_005625

203231_s_at

8

-2.09

0.0366

DEAD (Asp-Glu-Ala-Asp) box polypeptide 18

DDX18

NM_006773

205763_s_at

2

-1.9

0.0217

Eukaryotic translation initiation factor 4E binding protein 2

EIF4EBP2

U88989

224653_at

10

-1.89

0.0168

Serine/threonine kinase 38

STK38

NM_007271

1553117_a_at

6

-1.68

0.0196

Cyclin G2

CCNG2

AW134535

202769_at

4

-1.65

0.0129

S100 calcium binding protein A4

S100A4

NM_002961

203186_s_at

1

-1.62

0.0117

  1. Genes with greatest down regulation specific to Cyclin T2 or Cyclin T1 depletion. The 10 genes with greatest decrease in expression following Cyclin T2 or Cyclin T1 depletion are listed (p 0.05). All fold-changes are relative to MM control. Minimum expression level of genes in MM control was arbitrarily chosen as 3.0.