Figure 3

Effect of different divalent metals on hTDP2-mediated 5'-phosphotyrosyl bond cleavage reaction. (A) TDP2 (90 pM) was reacted with 5-sub (40 nM) under conditions similar to those described in Figure 2 with the exception of the addition of different divalent metal ions. (B) Data obtained in Panel A was plotted. Data represent mean values with standard error derived from three independent experiments.